Carboxylic Acids & Derivatives · Lecture Lecture · § 1 / 8
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Class XII · Chemistry · Unit 8 · Lecture

Carboxylic Acids & Derivatives

The full, readable lecture — the –COOH group and why it is acidic, salts and the CO₂ fizz, esterification, soap and the ester family, with their relative reactivity. As you scroll, the panel on the right shows each idea through an everyday object: vinegar, a lemon, a fizzing antacid, fruity perfume, a soap cauldron and an aspirin tablet.

Open a bottle of vinegar and the sharp, sour tang is acetic (ethanoic) acid, CH₃COOH — a carboxylic acid. Every carboxylic acid carries the same business end: the carboxyl group, –COOH, a carbonyl C=O joined to a hydroxyl –OH on one carbon. The general formula is RCOOH.

  • Carboxylic acid — an organic compound containing the carboxyl group –COOH (e.g. CH₃COOH, vinegar; HCOOH, the sting of an ant).
  • Carboxyl group — the C=O and –OH are not independent; they interact, and that is exactly what makes the –OH hydrogen acidic.
StructureIUPAC nameCommon / source
HCOOHmethanoic acidformic — ant & nettle sting
CH₃COOHethanoic acidacetic — vinegar
CH₃CH₂COOHpropanoic acidpropionic acid

IUPAC names end in -oic acid; the carboxyl carbon is always carbon number 1.

Bite a lemon and the puckering tartness is citric acid — a single molecule carrying three –COOH groups. In water each group lets its proton go:

ionisationR–COOH  ⇌  R–COO⁻  + H⁺

A carboxylic acid is far more acidic than an alcohol because the carboxylate ion RCOO⁻ is resonance-stabilised. Once the proton leaves, the negative charge is not stuck on one oxygen — it is shared equally over both oxygens:

two equivalent resonance formsR–C(=O)–O⁻  ⇌  R–C(–O⁻)=O
→ one ion, two identical C–O bonds, charge ½ on each O
Substituent effect: electron-withdrawing –Cl, –NO₂ spread the charge and increase acidity (Cl₃C–COOH ≫ CH₃COOH); electron-donating –CH₃ decreases it. Overall: acid > carbonic acid > phenol > water > alcohol.

Stir an antacid tablet or a spoon of baking soda into something acidic and it fizzes — that froth is carbon dioxide. As acids, –COOH compounds neutralise bases and react with carbonates:

with NaOH (neutralisation)R–COOH  + NaOH  →  R–COONa  + H₂O
with Na₂CO₃ / NaHCO₃ (fizz!)2 R–COOH  + Na₂CO₃  →  2 R–COONa  + H₂O  + CO₂↑
The brisk effervescence of CO₂ with sodium carbonate or bicarbonate is the classic confirmatory test for a –COOH group. Phenols do not fizz with NaHCO₃ — a handy way to tell them apart.

The fruity smell of a banana, a pineapple or a dab of perfume is an ester. A carboxylic acid reacts with an alcohol, over conc. H₂SO₄ as catalyst and dehydrating agent, to make one:

esterification (reversible)R–COOH  + R′OH  conc. H₂SO₄ / Δ⇌  R–COOR′  + H₂O

Isotope labelling shows the water comes from the –OH of the acid and the –H of the alcohol. It is an equilibrium: conc. H₂SO₄ removes the water (Le Chatelier), pulling the reaction toward more ester. Use the slider on the right to drive off water and watch the yield — and the smell — grow.

  • Ester — RCOOR′, from an acid + alcohol. Pleasant, fruity smells; used as flavours and fragrances. Aspirin is an ester too.

A fat is simply an ester — glycerol joined to three long fatty-acid chains. Boil it with NaOH (lye) in a cauldron and the ester links hydrolyse:

base hydrolysis = saponification (irreversible)fat (ester)  + 3 NaOH  →  3 R–COONa (soap)  + glycerol
Saponification gives soap (sodium salts of fatty acids) + glycerol. Acid hydrolysis (H⁺) is the reversible reverse of esterification; base hydrolysis runs to completion.

The tablet of aspirin in your medicine cabinet is an ester drug, made in industry by acylating salicylic acid. The fastest acylating agent is the acyl chloride, RCOCl — the –OH of the acid replaced by –Cl:

acyl chloride is a powerful acylating agentR–COCl + R′OH → ester (RCOOR′) + HCl
R–COCl + NH₃ → amide (RCONH₂) + HCl

Two more reactions of the acid itself: LiAlH₄ reduces –COOH all the way to a 1° alcohol; heating the sodium salt with soda-lime decarboxylates it, knocking out –COOH as carbonate.

reduction & decarboxylationR–COOH  LiAlH₄→  R–CH₂OH  (1° alcohol)
R–COONa + NaOH  CaO, Δ→  R–H + Na₂CO₃
  • Acid derivatives — replace the –OH of RCOOH with –Cl (acyl chloride), –OCOR (anhydride), –OR′ (ester) or –NH₂ (amide).

Picture four doors with locks of falling strength. The better the leaving group and the less the carbonyl is stabilised, the more reactive the derivative:

most reactive → least reactiveacyl chloride  >  anhydride  >  ester  >  amide

An acyl chloride has the best leaving group (Cl⁻), so it reacts fastest. An amide's nitrogen lone pair feeds into the carbonyl and stabilises it, so it reacts slowest. A more reactive derivative can always be converted into a less reactive one — never easily the reverse.

acidity order
Arrange in increasing acidity: CH₃COOH, ClCH₂COOH, HCOOH.
–CH₃ donates (weakest), –Cl withdraws (strongest):
CH₃COOH < HCOOH < ClCH₂COOH
  1. The –COOH group & –oic acid names; vinegar, lemon, ant sting.
  2. Acidity from the resonance-stabilised carboxylate; –Cl/–NO₂ up, –CH₃ down; acid > phenol > alcohol.
  3. Salts & the CO₂ fizz test; esterification (mechanism, conc. H₂SO₄).
  4. Esters → saponification → soap; reduction (LiAlH₄); decarboxylation.
  5. Derivatives & reactivity: acyl chloride > anhydride > ester > amide; aspirin is an ester.
⚛ Live panelCarboxylic Acids & Derivatives
Scroll the lecture — this panel shows each concept through an everyday object as you reach it.